ageless_genes

Ageless Genes™

$156.45

The nutrients in Ageless Genes™ protects and repairs mitochondria. There are three key nutrients that work together to support this vital cellular function. Arginine is in an extended-release form, creating superior absorption. Resveratrol in itself is poorly absorbed and quickly metabolized. Alpha lipoic acid is also blended in a sustained release formula for 12-hour activity.

60 Packets

Product Description

The Center For Natural Healing® Ageless Genes™ (AG) supplies three pharmacologically active, orally bioavailable nutraceutical formulas intended for use in promoting mitochondrial biogenesis. The nutraceuticals found in the AG are safe and well-tolerated and have been uniquely prepared to enhance both absorption and residence time in the body so as to maximize patient benefit and satisfaction. All Center For Natural Healing® formulas meet or exceed certified Good Manufacturing Process (cGMP) quality standards.

Patient Benefits

Used as directed, the Center For Natural Healing® Ageless Genes may help promote:

  • Improved insulin sensitivity and action
  • Improved glucose disposal
  • Increased Nitric Oxide (NO) production
  • Improved cardiovascular and endothelial function
  • Improved appetite control
  • Reduced fat mass
  • Increased muscle mass
  • Improved exercise performance
  • Improved antioxidant status and resistance to oxidative stress

Aging often feels like the body is slower and/or more tired. A certain part of our cells regulates how well we age — the mitochondria. Over 95% of our energy is produced here, and as we age, they depletes significantly. This is associated with multiple age-associated complications, deterioration and fatigue. Ageless Genes™ is formulated to preserve its effect on the body,  blended with quercitin and pterostilbene in order to achieve medicinal levels in our blood. Alpha lipoic acid is also blended in a sustained release formula for 12-hour activity. These three nutrients, taken together twice daily, offer cellular protection for the aging process, which is superior to any product on the market.

Discussion

Mitochondrial biogenesis is the process by which new mitochondria are produced. Representing ~10% of body weight, mitochondria are cellular “fuel stations” responsible for supplying >95% of the body’s energy needs, among other roles.[1] Mitochondrial biogenesis can delay aging and the onset of age-associated disease.[2-4] This complex process involves more than 1,000 genes[2] and is responsible for producing 20% of total cellular protein.[1] Exercise and caloric restriction are two of the most powerful means of stimulating mitochondrial biogenesis,[2,3] most notably by activating the “master regulator” of mitochondrial biogenesis and function and metabolic fitness known as PGC-1. PGC-1 is a transcriptional co-activator whose dysregulation has been implicated in aging and the pathogenesis of numerous age-associated diseases including but not limited to diabetes, obesity, sarcopenia and various neurological conditions.

PGC-1-deficient animals display defects of energy metabolism, glucose disposal and insulin action, as well as reduced resistance to oxidative stress, increased fat mass, decreased muscle mass, impaired exercise performance and other problems suggestive of an impaired ability to adapt to metabolic and physiological stress.[5] Conversely, PGC-1 activation contributes to an increase in metabolic fitness in the form of an increased metabolic rate; improved glucose disposal, fatty acid oxidation and insulin function; increased resistance to oxidative stress, decreased fat mass and increased muscle mass and exercise performance.

In addition to being awarded several U.S. patents, the nutraceuticals found in the AG have been clinically tested for their oral bioavailability, safety and efficacy in activating PGC-1 and upstream cellular signaling cascades (see diagram on other side), thereby mimicking the powerful protective effects of exercise and caloric restriction on mitochondrial biogenesis, metabolic fitness, aging and the onset of age-associated diseases.

The Ageless Genes (AG), consisting of Muscle Max™, Resveratrol™ and InsiMax™ contains pharmacologicallyactive, orally-bioavailable nutraceuticals that have been clinically tested for their safety and efficacy in stimulating key cellular signaling cascades involving Nitric Oxide (NO) (Muscle Max), SIRT1 (Resveratrol) and AMPK (InsiMax), among others. These pathways ultimately lead to the activation of PGC-1, the “master regulator” of mitochondrial biogenesis and function and metabolic fitness whose dysfunction has been associated with a number of age-associated diseases including but not limited to diabetes, obesity, sarcopenia and various neurological conditions.

References

1. Gofart and Wiesner (2003). Exp Physiol, 88(1): 33.
2. Lopez-Lluch G et al. (2008). Exp Gerontol, 43(9): 813.
3. Lanza IR et al. (2008). Diabetes, 57(11): 2933
4. Johnston AP et al. (2008). Appl Physiol Nutr Metab, 33(1): 191.
5. Leone et al. (2005). PLoS Biol, 3(4): e101.

These statements have not been evaluated by the FDA. This product is not intended to treat, diagnose, prevent, or cure any disease. Consult a physician before taking. Should you experience any serious physical side effects from taking these nutritional supplements, discontinue and call your doctor immediately.

Additional Information

Weight 1 lbs

Dosage

1 pack twice daily