Antioxidant Defense contains the amount of antioxidants you would receive in 5 cups of fruits and vegetables. It is used to minimize the effects free radicals on the body and the aging process. Made from organic pure Rosemary Extract. The antioxidant activity of fruits and vegetables are determined by the ORAC value (Oxygen Radical Absorbance Capacity). Studies have shown that an ORAC of 3000 or greater not only reduce age-related oxidative stress, but also improve neuronal and cognitive brain function. The ingredients in Antioxidant Defense™ are standardized to provide an ORAC of 6000.
- Antioxidant Support
- Minimize the Effect Free Radicals Have on the Aging Process
A relatively simple, but sensitive method that quantifies antioxidant capacity of foods and supplements is the Oxygen Radical Absorbance Capacity. The acronym for this assay is “ORAC”. The technique, developed by the National Institute of Aging and standardized by the USDA measures how well a sample inhibits an oxidizing agent and how long it takes to do so. The agent used as a standard control for antioxidant activity is a non-commercial, water-soluble derivative of tocopherol called Trolox. The units of an ORAC value are expressed as micromoles Trolox equivalents per gram of a substance (mmole TE/g).
The number of Trolox Equivalents that equate to eating an average of 5-9 servings of a variety of fruits and vegetables per day is 6000. The ORAC rating of approximately 3.5 ounces of prunes (5770), raisins (2830), blueberries (2400) and blackberries (2036) rank highest. An equivalent portion of foods such as eggplant (400), corn (390) and onion (450) have lower ratings. The ingredients in Antioxidant Defense® are standardized to provide 6000 TE/gram. Investigators in Spain found a 170-fold difference in ORAC values among seven commercial dietary antioxidant supplements.1
RosemarinX™, derived from the herb rosemary is manufactured using a proprietary extraction technology that selectively isolates the beneficial fraction of the rosemary herb. Center For Natural Healing® acquires RosemarinX™ from a source that uses ORAC values as part of its internal quality control and reports values for each lot. Studies have demonstrated the antioxidant, anti-carcinogenic and estrogen-modulating properties of rosemary.2,3,4
Berr-X™ comes from a blend of anthocyanin-rich berries that have high ORAC values. Studies have shown that berry anthocyanins not only reduce age-related oxidative stress, but also improve neuronal and cognitive brain function. Anthocyanin-rich berry extract formulas have been shown to have antioxidant, anti-carcinogenic and anti-angiogenic effects.5,6
1. Davalos A, Gomez-Cordoves C, Bartolome B. Extending applicability of the oxygen radical absorbance capacity (ORAC-flourescein) assay. J Agric Food Chem. 2004 Jan 14;52(1):48-54
2. Steiner M, Priel I, Giat J, Levy J, Sharoni Y, Danilenoko M. Carnosic acid inhibits proliferation and augments differentiation of human leukemic cells induced by 1,25-dihydroxyvitamin D3 and retinoic acid. Nutr Cancer 2001:41(1-2):135-44
3. Offord EA, Mace K, Avanti O, Pfeifer AM. Mechanisms involved in the chemoprotective effects of rosemary extract studied in human liver and bronchial cells. Cancer Letter 1997 Mar 19; 114(1-2):275-81
4. Zhu BT. Dietary administration of an extract from rosemary leaves enhances the liver microsomal metabolism of endogenous estrogens and decreases their uterotropic action in CD-1 mice. [PMID: 9806165]
5. Bagchi D, Sen CK, Bagchi M, Atalay M. Anti-angiogenic, antioxidant and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Mosc)2004 Jan:69(1):75-80
6. Seeram NP, et al. Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro. J Agric Food Chem. 2006 Dec 13;54(25):9329-9339. [PMID: 17147415].
7. Halvorsen BL, et al. Content of redix-active compounds (ie, antioxidants) in foods consumed in the United States. Am J Clin Nutr. 2006 Jul;84(1):95-135 [PMID: 16825686]
8. Zheng W, Wang SY. Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries. J Agric Food Chem. 2003 Jan 15;51(2):502-9 [PMID: 12517117]
9. Prior RL, et al. Identification of procyanidins and anthocyanins in blueberries and cranberries (Vaccinium spp.) using high-performance liquid chromatography/mass spectrometry. J Agric Food Chem. 2001 Mar;49(3):1270-6 [PMID: 11312849]
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.